~~ 2023 ~~
September 30, 2023
Undergraduate Riya joins us to get some hands-on experience with the exciting world of septins. Welcome aboard!
September 1, 2023
Lab member Andy joined the team! Welcome to the Spiliotis Lab.
July, 2023
The lab is taking shape at the University of Virginia as members Franklin, Noor and Aisha start working. Ben holds down the fort at Drexel.
~~ 2020 ~~
August, 2020
Our new website is up and live! Big thanks to Josh for doing an awesome job putting it together.
June 17, 2020
Iliana will be speaking and presenting her work on Septin 9 and Dynein on July 23 at the international on-line membrane trafficking
seminar series.
June 16, 2020
Excited for the inaugural septin paper by our Drexel colleague and collaborator
Shae Padrick.
The preprint entitled
"Production and analysis of a mammalian septin hetero-octamer complex"
is now available on BioRxiv, and describes a new purification scheme for the preparation of SEPT2/6/7/3 complexes. In addition, it shows that SEPT3 occupies the central position in the hetero-octamer.
June 5, 2020
It took COVID-19 to finally join and get our lab on
Slack.
Looking forward to our new mode of communication and sharing new papers/pubs as they come across our radar.
June 3, 2020
We are appalled and disgusted by the recent murder of George Floyd and the systemic racism and police brutality that's been plaguing our country for ages.
We stand in solidarity and support with the protests, and the national cry for justice, real change and reform.
Black Lives Matter!
June 2, 2020
Iliana's paper on SEPT9 and dynein is submitted and live on
BioRxiv
!
June 1, 2020
We are funded with the R35 grant GM136337 ($1,817,463) for five years from the
National Institute of General Medical Sciences
(NIH). Grateful to all current and past members of the lab that helped making this achievement possible. Looking forward to another five years of exciting science.
March 18, 2020
Lab suspends operations due to COVID-19. We will be working from home until further notice. Hope everyone stays safe and healthy during this challenging time. We will be analyzing data, writing papers and reviews remotely and meeting on-line.
March 5, 2020
Elias is visiting
Bennington College
in Vermont, hosted by friend and colleague Amie McClellan.
March 3, 2020
Elias is in Boston at a seminar talk visit in the
Department of Biology of Brandeis University.
~~ 2019 ~~
Dec 12, 2019
Check out this super cool video abstract that Kostas made with Science Sketches on his
MBoC paper.
Dec 10, 2019
Reuniting with lab alums Lee Dolat and Eva Karasmanis for ASCB lab dinner at
Zaytinya
of the amazing Chef Jose Andres.
Dec 6, 2019
We are in Washington, DC for the 2019 annual meeting of ASCB/EMBO. Check out our four posters and two talks. Full schedule of our presentations as follows:
Sunday:
Talk (Room 207B – 6:35 pm) and poster (P487/B499) by Megan Radler
Poster (P154/B158) by Kostas Nakos Monday:
Talk by Iliana Kesisova (Room 145A – 5:55 pm) Tuesday:
Poster (P1882/B122)by Iliana Kesisova
Poster (P2416/B670) by Josh Okletey
Talk (Room 207B – 6:35 pm) and poster (P487/B499) by Megan Radler
Poster (P154/B158) by Kostas Nakos Monday:
Talk by Iliana Kesisova (Room 145A – 5:55 pm) Tuesday:
Poster (P1882/B122)by Iliana Kesisova
Poster (P2416/B670) by Josh Okletey
Nov 15, 2019
Congratulations to Kostas! His paper is featured on the
cover of the
November 15 issue of Molecular Biology of the Cell.
Nov 4, 2019
Awesome news! R35 grant application receives the nearly perfect impact score of… 11! Woah! Humbled by the reviewers' response and all the hard work of current and previous members of the lab that led to this success. Time to celebrate and party!
Oct 31, 2019
Kostas's and Megan's paper
"Septin 2/6/7 complexes tune microtubule plus-end growth and EB1 binding in a concentration- and filament-dependent manner"
is now published in Molecular Biology of the Cell.
Sept 26, 2019
We're on a streak of good news! Elias found that his application for a Drexel CURE grant from the PA Department of Health was selected for funding. The proposal is on Megan's neurite project – thank you and congrats Megan! - and in collaboration with
Kazu Toyooka
from the department of Neurobiology and Anatomy, and
Lin Han
from the School of Biomedical Engineering, Science and Health Systems. The project is slated to begin in the summer of 2020.
Sept 25, 2019
Kostas's and Megan's paper is now accepted in Molecular Biology of the Cell. Congratulations Kostas and Megan!
Sept 25, 2019
Megan Radler has been awarded a travel award from the Biology Department to attend the 2019 annual meeting of the American Society for Cell Biology.
Sept 4, 2019
Exciting news: Megan's and Iliana's abstracts were picked for minisymposia talks at the 2019 annual meeting of ASCB! Woohoo!
July 30, 2019
Elias is attending and presenting our work at the
2019 Motile & Contractile Systems Gordon Research Conference
at Colby-Sawyer College in New Hampshire. Elias is giving a talk on the spatial control of microtubule dynamics and microtubule-dependent traffic by septins.
July 8, 2019
Eva's paper is published in
today's issue of Current Biology.
June 27, 2019
Magan Radler wins first place award in our department's annual BioImage contest! Congrats Megan!
Jun 13, 2019
Our Current Biology paper
"A septin double ring controls the spatiotemporal organization of the ESCRT machinery in cytokinetic abscission" is now available on-line.It's scheduled for the July 8 issue of Current Biology.
May 31, 2019
Farewell dinner for Eva & Jimmy at
Isot restaurant
(authentic Turkish), which won us instantly with its amazing food and let us do (Megan's) jello shots for dessert! Good luck to Eva and Jimmy! Thankful for being part of our journey. We will miss you.
May 14, 2019
Kostas and Megan completed a
new manuscript
ion the regulation of microtubule plus end growth and EB1 binding by SEPT2/6/7 and it's now available on bioRxiv. Check it out!
Apr 25, 2019
Congrats Dr. Karasmanis! Eva has successfully defended her PhD. She's moving on to a postdoctoral fellowship with Dr. Sam Reck-Peterson (UCSD/HHMI).
Eva's graduating with a total of eight publications including first author research papers in Developmental Cell, Current Biology and Molecular Biology of the Cell. A total rock star, who will be sorely missed!
Apr 14, 2019
Elias is giving a talk and chairing a session at the
5th EMBO Workshop on Emerging Concepts of the Neuronal Cytoskeleton
in Villarica, Chile. Check out these amazing "rockstar" photos of all the speakers taken by the incredibly talented photographer
Rodo Carvajol. Check it out
Apr 1, 2019
Undergraduate Brenna Doyle is joining us for a 6-month coop. Looking forward to working with Brenna. We always wanted a philosophy minor in the lab to talk about Michel Foucault's work along with neuronal cell biology.
Mar 12, 2019
We're hosting
Shirin Bahmanyar
from Yale University
Catch Dr. Bahmanyar's seminar "ER size and shape and its role in nuclear envelope dynamics" in PISB 104 at 3:30 pm. Shirin and Elias go back to their beginnings as a grad student and post-doc, respectively, in James Nelson's lab at Stanford in the early 2000s.
Mar 8, 2019
Eva is featured by the American Society for Cell Biology (ASCB) in a
Member News/Profile article by Mary Spiro.
Mar 5, 2019
Lou's manuscript
"Proteomic profiling of the oncogenic septin 9 reveals isoform-specific interactions in breast cancer cells" is now available on BioXriv.
Jan 11, 2019
Elias is a Co-Investigator on two CURE grant awards from the Pennsylvania Department of Health:
- Control of Actin Dynamics by Disease-linked Septin Isoforms and Mutants (PI: Shae Padrick)
- Human Organoid Technology as the Next Generation Approach to Examine Tau-based Mechanisms and Therapies for Gulf War Illness (PI: Oscar Liang)
~~ 2018 ~~
Dec 13, 2018
Excited about our collaboration with Serge Mostowy's lab on this Shigella-septin study, which is now published in Cell Host & Microbe:
"Septins recognize and entrap dividing bacterial cells for delivery to lysosomes".
Dec, 2018
We are in sunny San Diego for the annual meeting of the American Society for Cell Biology. We've got several poster presentations. Come find us to learn about our work.
Sunday: Iliana (B141/P1138) and Eva (B491/P1480)
Monday: Lou (B36/P1899)
Tuesday: Posters by Iliana(B139/P2902) and Eva (B235/P2895)
Oct 15, 2018
We welcome Joshua Okletey as our lab's new technician. Welcome aboard Josh!
Aug 23, 2018
Elias was awarded an equipment supplement of $134,195 from NIH/NIGMS for putting together a spinning disk confocal microscopy system with photomanipulation capabilities.
July, 2018
It's Gordon Research Conference season! Eva and Megan are attending the
Cell Biology of the Neuron
GRCin Waterville Valley, New Hampshire. Eva is giving a talkon Monday morning and Megan is presenting a poster. Elias is attending and presenting posters at the Lysosomes & Endocytosis
(Proctor Academy, Andover, New Hampshire) and Cytoskeletal Motors (West Dover, Vermont) GRCs.
May 22, 2018
Congrats to Eva for being awarded the
2018 Drexel University Research Excellence Award the post-candidacy category. She's being awarded $750 and recognized at the Graduate Student Day awards ceremony on Thursday March31, 2018 at 4 pm in the Mitchell Auditorium.
May 4, 2018
Elias is awarded a 2018 Scholarly Material & Research Equipment Award ($30,000) for retrofitting an Olympus IX83 microscope with a spinning disk confocal scan head.
Apr 15, 2018
We welcome Harini Sreenivasappa as the new manager of the Cell Imaging Center.Harini is joining us from Texas A&M University (College Station, TX) where she did her PhD and post-doctoral studies in the lab of
Dr. Andreea Trache.
Feb 2, 2018
Elias has been awarded a CURE grant for the project "Role of SEPT9 in breast cancer metastasis", a collaboration with the lab of
Dr. Mauricio Reginato (Co-Investigator) at Drexel College of Medicine.